Methuselah Flies Project

Rejuve Biotech's flagship project is the study of the longest-living drosophila melanogaster fruit flies, also known as "Methuselah Flies," in collaboration with Genescient Corporation. These flies, which share 60% of their overall genome with humans, and 75% of disease-causing genes, live up to 5 times longer than normal fruit flies, according to a ten-year study. These flies are classified into three groups: 1) Control flies (30 days), 2) O flies (75 days, living 2.5x longer than normal flies), and 3) Super O flies (150 days, living 5x longer than normal flies, continuously bred for increasingly longer lifespans).

By analyzing human genome data collected and electively shared by Rejuve Network members via the Longevity mobile app and using advanced AI tools, Rejuve Network and Biotech scientists can identify which factors are responsible for increased lifespan, and if and how these same factors could be transferable to human longevity science.